Article
Susceptibility to mycobacterial disease due to mutations in IL-12Rβ1 in three Iranian patients.
Immunogenetics - 1 Jun 2018
Alinejad Dizaj Maryam, Mortaz Esmaeil, Mahdaviani Seyed Alireza, Mansouri Davood, Mehrian Payam, Verhard Els M, Varahram Mohammad, Babaie Delara, Adcock Ian M, Garssen Johan, van de Vosse Esther, Velayati Aliakbar
Abstract excerpt
In the last decade, autosomal recessive interleukin-12 receptor β1 (IL-12Rβ1) deficiency, the most common cause of Mendelian susceptibility to mycobacterial disease (MSMD), has been diagnosed in a few children and adults with severe tuberculosis in Iran. Here, we report three cases referred to the Immunology, Asthma and Allergy ward at the National Research Institute of Tuberculosis and Lung Diseases (NRITLD) at...
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