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Article

Genetic screening of regulatory regions of pituitary transcription factors in patients with idiopathic pituitary hormone deficiencies.

Pituitary - 1 Feb 2018

Elizabeth Melitza, Hokken-Koelega Anita C S, Schuilwerve Joyce, Peeters Robin P, Visser Theo J, de Graaff Laura C G

Abstract excerpt

PURPOSE: Mutation frequencies of PROP1, POU1F1 and HESX1 in patients with combined pituitary hormone deficiencies (CPHD) vary substantially between populations. They are low in sporadic CPHD patients in Western Europe. However, most clinicians still routinely send DNA of their CPHD patients for genetic screening of these pituitary transcription factors. Before we can recommend against screening of PROP1, POU1F1...

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Source

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Identifiers

PMID: 29255988
DOI: 10.1007/s11102-017-0850-6
PMCID: PMC5767207

Genes

HESX1
PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic screening of regulatory regions of pituitary transcription factors in patients with idiopathic pituitary hormone deficiencies.PMID 29255988Read ↗

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