Article
Effect of non-β-lactams on stable variants of inhibitor-resistant TEM β-lactamase in uropathogenic Escherichia coli: implication for alternative therapy.
Journal of applied microbiology - 1 Mar 2018
Mukherjee S K, Mandal R S, Das S, Mukherjee M
Abstract excerpt
AIMS: β-lactamase inhibitor resistance (BLIR) among the uropathogenic Escherichia coli (UPEC) minimizes treatment options. This study aimed to identify inhibitor-resistant TEM (IRT) β-lactamase that impart BLIR phenotype and explore non-β-lactams as alternative therapeutics. METHODS AND RESULTS: Thirty BLIR UPEC isolates were detected by Kirby-Bauer disc diffusion technique using β-lactam-β-lactamase inhibitor...
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