Article
Genome Sequencing Links Persistent Outbreak of Legionellosis in Sydney (New South Wales, Australia) to an Emerging Clone of Legionella pneumophila Sequence Type 211.
Applied and environmental microbiology - 1 Mar 2018
Timms Verlaine J, Rockett Rebecca, Bachmann Nathan L, Martinez Elena, Wang Qinning, Chen Sharon C-A, Jeoffreys Neisha, Howard Peter J, Smith Anna, Adamson Sheena, Gilmour Robin, Sheppeard Vicky, Sintchenko Vitali
Abstract excerpt
The city of Sydney, Australia, experienced a persistent outbreak of Legionella pneumophila serogroup 1 (Lp1) pneumonia in 2016. To elucidate the source and guide public health actions, the genomes of clinical and environmental Lp1 isolates recovered over 7 weeks were examined. A total of 48 isolates from human cases and cooling towers were sequenced and compared using single-nucleotide polymorphism (SNP)-based...
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