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Article

Human mesenchymal stromal cell therapy for damaged cochlea repair in nod-scid mice deafened with kanamycin.

Cytotherapy - 1 Feb 2018

Bettini Simone, Franceschini Valeria, Astolfi Laura, Simoni Edi, Mazzanti Benedetta, Martini Alessandro, Revoltella Roberto P

Abstract excerpt

BACKGROUND: Kanamycin, mainly used in the treatment of drug-resistant-tuberculosis, is known to cause irreversible hearing loss. Using the xeno-transplant model, we compared both in vitro and in vivo characteristics of human mesenchymal stromal cells (MSCs) derived from adult tissues, bone marrow (BM-MSCs) and adipose tissue (ADSCs). These tissues were selected for their availability, in vitro multipotency and...

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Identifiers

PMID: 29246648
DOI: 10.1016/j.jcyt.2017.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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