Article
Genetic variation and co-evolutionary relationship of RNA polymerase complex segments in influenza A viruses.
Virology - 1 Nov 2017
Chen Wentian, Xu Qi, Zhong Yaogang, Yu Hanjie, Shu Jian, Ma Tianran, Li Zheng
Abstract excerpt
The RNA polymerase complex (RNApc) in influenza A viruses (IVs) is composed of the PB2, PB1 and PA subunits, which are encoded by the three longest genome segments (Seg1-3) and are responsible for the replication of vRNAs and transcription of viral mRNAs. However, the co-evolutionary relationships of the three segments from the known 126 subtypes IVs are unclear. In this study, we performed a detailed analysis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.