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A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults

13 Dec 2017

Abstract excerpt

BACKGROUND: MenB-FHbp is a licensed meningococcal B vaccine targeting factor H-binding protein. Two phase 3 studies assessed the safety of the vaccine and its immunogenicity against diverse strains of group B meningococcus. METHODS: We randomly assigned 3596 adolescents (10 to 18 years of age) to receive MenB-FHbp or hepatitis A virus vaccine and saline and assigned 3304 young adults (18 to 25 years of age) to...

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PMID: 29236639
DOI: 10.1056/nejmoa1614474

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