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Article

EBV‐encoded miRNAs target ATM‐mediated response in nasopharyngeal carcinoma

12 Dec 2017

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a highly invasive epithelial malignancy that is prevalent in southern China and Southeast Asia. It is consistently associated with latent Epstein-Barr virus (EBV) infection. In NPC, miR-BARTs, the EBV-encoded miRNAs derived from BamH1-A rightward transcripts, are abundantly expressed and contribute to cancer development by targeting various cellular and viral genes. In this...

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PMID: 29230817
DOI: 10.1002/path.5018

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