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Article

11C-CFT-PET in Presymptomatic FTDP-17: A Potential Biomarker Predicting Onset.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Wu Liyong, Liu Jia, Feng Xueyan, Dong Jing, Qin Wei, Liu Yang, Wang Jingjuan, Lu Jie, Chen Kewei, Wang Yuping, Jia Jianping

Abstract excerpt

Frontotemporal dementia with parkinsonism-linked to chromosome 17 (FTDP-17) is a rare autosomal dominant neurodegenerative disorder. Most patients with FTDP-17 carry the mutation in the microtubule-associated protein tau (MAPT) gene. Striatum is predominantly and early affected in FTDP-17. Five family members (two symptomatic patients and three presymptomatic mutation carriers) from a Chinese pedigree of FTDP-17...

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Identifiers

PMID: 29226866
DOI: 10.3233/JAD-170561

Genes

MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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