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Article

Elevation of autophagy markers in Sjögren syndrome dry eye

4 Dec 2017

Abstract excerpt

Autophagy is known to be implicated in the pathogenesis of Sjögren syndrome (SS), but evidences are limited. We aimed to examine the levels of autophagy markers in tear film and conjunctival epithelial cells from SS dry eye patients, and analyze their correlations with clinical features. Patients with SS dry eye exhibited lower Schirmer values, lower tear breakup time, and higher ocular staining scores. In tears,...

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PMID: 29222450
DOI: 10.1038/s41598-017-17128-0

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