Article
Breast cancer: The translation of big genomic data to cancer precision medicine.
Cancer science - 1 Mar 2018
Low Siew-Kee, Zembutsu Hitoshi, Nakamura Yusuke
Abstract excerpt
Cancer is a complex genetic disease that develops from the accumulation of genomic alterations in which germline variations predispose individuals to cancer and somatic alterations initiate and trigger the progression of cancer. For the past 2 decades, genomic research has advanced remarkably, evolving from single-gene to whole-genome screening by using genome-wide association study and next-generation sequencing...
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