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Article

Association of Cx43 rs2071166 polymorphism with an increased risk for atrial septal defect.

Cardiology in the young - 1 Mar 2018

Gu Ruoyi, Sheng Wei, Ma Xiaojing, Huang Guoying

Abstract excerpt

Atrial septal defect is one of the most common CHD. The pathogenesis of atrial septal defect still remains unknown. Cx43 is the most prevalent connexin in the mammalian heart during development. Its genetic variants can cause several CHD. The aim of our study was to investigate the association of genetic variations of the Cx43 with sporadic atrial septal defect. A total of 450 paediatric patients were recruited,...

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PMID: 29198211
DOI: 10.1017/S1047951117002001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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