Article
Immune and Imaging Correlates of Mild Cognitive Impairment Conversion to Alzheimer's Disease.
Scientific reports - 1 Dec 2017
La Rosa Francesca, Saresella Marina, Baglio Francesca, Piancone Federica, Marventano Ivana, Calabrese Elena, Nemni Raffaello, Ripamonti Enrico, Cabinio Monia, Clerici Mario
Abstract excerpt
Amnestic mild cognitive impairment (aMCI) conversion to Alzheimer's disease (AD) is seen in a sizable portion of aMCI patients; correlates predicting such conversion are poorly defined but neuroinflammation and the reactivation of chronic viral infections are suspected to play a role in this phenomenon. We analyzed these aspects in two homogeneous groups of aMCI who did or did not convert to AD over a 24-months...
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