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Expressed fusion gene landscape and its impact in multiple myeloma

27 Nov 2017

Abstract excerpt

Multiple myeloma is a plasma cell malignancy characterized by recurrent IgH translocations and well described genomic heterogeneity. Although transcriptome profiles in multiple myeloma has been described, landscape of expressed fusion genes and their clinical impact remains unknown. To provide a comprehensive and detailed fusion gene cartography and suggest new mechanisms of tumorigenesis in multiple myeloma, we...

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PMID: 29196615
DOI: 10.1038/s41467-017-00638-w

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