Article
Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.
Translational psychiatry - 30 Nov 2017
Morey Rajendra A, Davis Sarah L, Garrett Melanie E, Haswell Courtney C, Marx Christine E, Beckham Jean C, McCarthy Gregory, Hauser Michael A, Ashley-Koch Allison E
Abstract excerpt
Depending on the traumatic event, a significant fraction of trauma survivors subsequently develop PTSD. The additional variability in PTSD risk is expected to arise from genetic susceptibility. Unfortunately, several genome-wide association studies (GWAS) have failed to identify a consistent genetic marker for PTSD. The heritability of intermediate phenotypes such as regional brain volumes is often 80% or higher....
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