Article
Plant-type phytoene desaturase: Functional evaluation of structural implications.
PloS one - 1 Jan 2017
Koschmieder Julian, Fehling-Kaschek Mirjam, Schaub Patrick, Ghisla Sandro, Brausemann Anton, Timmer Jens, Beyer Peter
Abstract excerpt
Phytoene desaturase (PDS) is an essential plant carotenoid biosynthetic enzyme and a prominent target of certain inhibitors, such as norflurazon, acting as bleaching herbicides. PDS catalyzes the introduction of two double bonds into 15-cis-phytoene, yielding 9,15,9'-tri-cis-ζ-carotene via the intermediate 9,15-di-cis-phytofluene. We present the necessary data to scrutinize functional implications inferred from...
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