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Article

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients

21 Nov 2017

Abstract excerpt

The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric disorders has fostered new conceptual and clinical frameworks. However, detection reliability, putative presence in different diseases and in health have raised questions about potential pathogenic mechanism mediated by autoantibodies. Using a combination of single molecule-based imaging approaches, we here ascertain...

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PMID: 29176681
DOI: 10.1038/s41467-017-01700-3

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