Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts.

doi:10.1016/j.jaac.2017.09.428

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Article

Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Dec 2017

Wilcox Holly C, Fullerton Janice M, Glowinski Anne L, Benke Kelly, Kamali Masoud, Hulvershorn Leslie A, Stapp Emma K, Edenberg Howard J, Roberts Gloria M P, Ghaziuddin Neera, Fisher Carrie, Brucksch Christine, Frankland Andrew, Toma Claudio, Shaw Alex D, Kastelic Elizabeth, Miller Leslie, McInnis Melvin G, Mitchell Philip B, Nurnberger John I

Abstract excerpt

OBJECTIVE: Bipolar disorder (BD) is one of the most heritable psychiatric conditions and is associated with high suicide risk. To explore the reasons for this link, this study examined the interaction between traumatic stress and BD polygenic risk score in relation to suicidal ideation, suicide attempt, and nonsuicidal self-injury (NSSI) in adolescent and young adult offspring and relatives of persons with BD...

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Identifiers

PMID: 29173741
DOI: 10.1016/j.jaac.2017.09.428
PMCID: PMC5797709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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