Article
Are VNTRs co-localizing with breast cancer-associated SNPs?
Breast cancer research and treatment - 1 Feb 2018
Leclerc Martin, Neuhausen Susan L, Schayek Hagit, Laitman Yael, Antonis Antoniou C, Friedman Eitan
Abstract excerpt
PURPOSE: Several common genetic variants (single-nucleotide polymorphisms, SNPs) have been shown to be associated with breast cancer (BC) risk in the general population, and to modify BC risk for BRCA1 and BRCA2 mutation carriers. Co-localization of variable number of tandem repeats (VNTRs) with these BC-associated SNPS has not been comprehensively studied. METHODS: Cross referencing of genome-wide VNTRs with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.