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Article

Estimating virus effective population size and selection without neutral markers.

PLoS pathogens - 1 Nov 2017

Rousseau Elsa, Moury Benoît, Mailleret Ludovic, Senoussi Rachid, Palloix Alain, Simon Vincent, Valière Sophie, Grognard Frédéric, Fabre Frédéric

Abstract excerpt

By combining high-throughput sequencing (HTS) with experimental evolution, we can observe the within-host dynamics of pathogen variants of biomedical or ecological interest. We studied the evolutionary dynamics of five variants of Potato virus Y (PVY) in 15 doubled-haploid lines of pepper. All plants were inoculated with the same mixture of virus variants and variant frequencies were determined by HTS in eight...

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Identifiers

PMID: 29155894
DOI: 10.1371/journal.ppat.1006702
PMCID: PMC5720836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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