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Article

Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

16 Nov 2017

Abstract excerpt

Prostate cancer research is hampered by the lack of in vivo preclinical models that accurately reflect patient tumour biology and the clinical heterogeneity of human prostate cancer. To overcome these limitations we propagated and characterised a new collection of patient-derived prostate cancer xenografts. Tumour fragments from 147 unsupervised, surgical prostate samples were implanted subcutaneously into...

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PMID: 29145505
DOI: 10.1371/journal.pone.0188228

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