Article
HIV-1 resistance rarely observed in patients using darunavir once-daily regimens across clinical studies.
HIV clinical trials - 1 Jan 2000
Lathouwers Erkki, Wong Eric Y, Luo Donghan, Seyedkazemi Sareh, De Meyer Sandra, Brown Kimberley
Abstract excerpt
BACKGROUND: Darunavir 800 mg once daily (QD) is indicated for HIV-1-infected treatment-naïve and treatment-experienced (without darunavir resistance-associated mutations [RAMs]) individuals, and has been evaluated in phase 2/3 studies with durations between 48 and 192 weeks. OBJECTIVE: To summarize the development (or identification) of post-baseline resistance (RAMs and antiretroviral phenotypic susceptibility)...
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