Article
Trends in darunavir resistance-associated mutations and phenotypic resistance in commercially tested United States clinical samples between 2006 and 2012.
AIDS research and human retroviruses - 1 Jun 2015
Lathouwers Erkki, Gupta Soumi, Haddad Mojgan, Paquet Agnes, de Meyer Sandra, Baugh Bryan
Abstract excerpt
HIV-1 samples submitted by clinicians from the United States for routine drug susceptibility testing (PhenoSense GT) were evaluated for genotypic and phenotypic resistance to darunavir and other protease inhibitors (PIs). Among these samples (Monogram Biosciences database January 2006-June 2012; N=78,843), isolates harboring zero IAS-USA darunavir resistance-associated mutations (RAMs) increased from 77.7% in...
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