Article
Virological analysis of once-daily and twice-daily darunavir/ritonavir in the ODIN trial of treatment-experienced patients.
Antiviral therapy - 1 Jan 2013
Lathouwers Erkki, De La Rosa Guy, Van de Casteele Tom, Baeten Benny, Tomaka Frank, De Meyer Sandra, Picchio Gaston
Abstract excerpt
BACKGROUND: The aim of this analysis was to characterize viral resistance in the Phase III, randomized ODIN trial, which demonstrated non-inferiority of once-daily darunavir/ritonavir (DRV/r) 800/100 mg to DRV/r 600/100 mg twice daily, each combined with an optimized background regimen in treatment-experienced patients with no DRV resistance-associated mutations (RAMs) at screening. METHODS: Virological failure...
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