Article
Generation of induced pluripotent stem cell line (ZZUi005-A) from a 21-year-old patient with a novel RAB39B gene mutation in X-linked juvenile parkinsonism.
Stem cell research - 1 Dec 2017
Wang Yanlin, Sun Huifang, Wang Zhilei, Yang Zhihua, Shi Mengmeng, Yang Jing, Liu Yutao, Liu Han, Zhang Shuo, Shi Changhe, Xu Yuming
Abstract excerpt
Ras-related protein 39B (RAB39B) mutation has been reported as a potential cause of X-linked Parkinson's disease (PD), a rare form of familial PD. Recently, a novel RAB39B mutation was identified in an X-linked juvenile parkinsonism family and the dermal fibroblasts of the patient were obtained and successfully induced to induced pluripotent stem cells (iPSCs) by the human OSKM transcription factors using the...
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