Article
A genetic variant of miR-335 binding site in the ERBB4 3'-UTR is associated with prognosis of ovary cancer.
Journal of cellular biochemistry - 1 Jul 2018
Wei Ping, Li Ling, Zhang Zhihu, Zhang Wei, Liu Ming, Sheng Xiugui
Abstract excerpt
Ovarian cancer is one of the leading gynecologic malignancies globally, the 5-year survival rate for patients with advanced stage ovarian cancer is very low. Our objective was to test the hypothesis that miR-335 was associated with the survival of patients with ovarian cancer. Bioinformatics tools and luciferase report assay were used to select the target of miR-335, and real-time PCR was used to detect the...
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