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Article

Molecular Characteristics of Conjunctival Melanoma Using Whole-Exome Sequencing

9 Nov 2017

Abstract excerpt

Importance: Conjunctival melanoma (CM) is a highly aggressive ocular cancer for which treatment options are limited; the molecular pathogenesis is poorly understood. Objective: To identify the molecular characteristics of CM using next-generation whole-exome sequencing (WES). Design, Setting, and Participants: Whole-exome sequencing was performed on tumor DNA extracted from the archived specimens of 5 patients...

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PMID: 29121185
DOI: 10.1001/jamaophthalmol.2017.4837

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