Article
Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism.
Atherosclerosis - 1 Dec 2017
Wolska Anna, Dunbar Richard L, Freeman Lita A, Ueda Masako, Amar Marcelo J, Sviridov Denis O, Remaley Alan T
Abstract excerpt
Apolipoprotein C-II (apoC-II) is a small exchangeable apolipoprotein found on triglyceride-rich lipoproteins (TRL), such as chylomicrons (CM) and very low-density lipoproteins (VLDL), and on high-density lipoproteins (HDL), particularly during fasting. ApoC-II plays a critical role in TRL metabolism by acting as a cofactor of lipoprotein lipase (LPL), the main enzyme that hydrolyses plasma triglycerides (TG) on...
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