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Characterization of Recombinant Flaviviridae Viruses Possessing a Small Reporter Tag

1 Nov 2017

Abstract excerpt

ABSTRACT The family Flaviviridae consists of four genera, Flavivirus , Pestivirus , Pegivirus , and Hepacivirus , and comprises important pathogens of human and animals. Although the construction of recombinant viruses carrying reporter genes encoding fluorescent and bioluminescent proteins has been reported, the stable insertion of foreign genes into viral genomes retaining infectivity remains difficult. Here,...

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PMID: 29093094
DOI: 10.1128/jvi.01582-17

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