[Genome editing ~Principle and possibility of a novel genetic engineering technology. Basic principles of genome editing.]

doi:CliCa171116381644

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Article

[Genome editing ~Principle and possibility of a novel genetic engineering technology. Basic principles of genome editing.]

Clinical calcium - 1 Jan 2000

Yamamoto Takashi

Abstract excerpt

Programmable site-specific nuclease mediated-genome editing is an emerging biotechnology for precise manipulation of target genes. In genome editing, gene-knockout as well as gene-knockin are possible in various organisms and cultured cells. CRISPR-Cas9, which was developed in 2012, is a convenient and efficient programmable site-specific nuclease and the use spreads around the world rapidly. For this, it is...

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PMID: 29074838
DOI: CliCa171116381644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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