Article
[Genome engineering using the CRISPR-Cas9 system and applications in cancer research].
Magyar onkologia - 20 Jul 2018
Hudacsek Viktória, Gyõrffy Balázs
Abstract excerpt
Today, we have to investigate the effects of selected mutations and molecular alterations - this is made possible by the new genome editing technologies. In these, either a section of the DNA is deleted or moved, or a targeted mutation is introduced into the cell. Here, we describe in detail the CRISPR-Cas9 genome editing method. The technology is based on a feature used by bacteria to combat recurrent viral...
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