Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles.

Clinics (Sao Paulo, Brazil) - 1 Oct 2017

De-Marco Viviani, Carvalho Luciani R, Guzzo Mariana F, Oliveira Paulo S L, Gomes Larissa G, Mendonca Berenice B

Abstract excerpt

OBJECTIVES: Pituitary-dependent hyperadrenocorticism is the most common cause of naturally occurring hypercortisolism in dogs. CRHR1 expression in human and dog corticotrophinomas suggested that this gene affects pituitary tumorigenesis. The present study aimed to investigate mutations in the CRHR1 coding region in poodles with pituitary-dependent hyperadrenocorticism. METHODS: Fifty poodles with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenocorticotropic Hormone
Share to Analysis of Variance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRF Receptor, Type 1

Share to Genetic Association Studies

Share to Pituitary Gland

Share to Receptors, Corticotropin-Releasing Hormone

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29069262
DOI: 10.6061/clinics/2017(09)09
PMCID: PMC5629736

Genes

CRHR1
CRH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles.PMID 29069262Read ↗

Functional characterization of canine wild type glucocorticoid receptor and an insertional mutation in a dog.Semantic proximity Read ↗

Corticotropinoma as a Component of Carney ComplexSemantic proximity Read ↗

Impaired Adrenocorticotropin-Adrenal Axis in Combined Pituitary Hormone Deficiency Caused by a Two-Base Pair Deletion (301–302delAG) in the Prophet of Pit-1 Gene<sup>1</sup>Semantic proximity Read ↗

Hereditary 1,25-dihydroxyvitamin D-resistant rickets in a Pomeranian dog caused by a novel mutation in the vitamin D receptor gene.Semantic proximity Read ↗

Lack of Ubiquitin Specific Protease 8 (USP8) Mutations in Canine Corticotroph Pituitary Adenomas.Semantic proximity Read ↗

Effect of 3 NR3C1 Mutations in the Pathogenesis of Pituitary ACTH AdenomaSemantic proximity Read ↗

Clinical features and heritability of hypoadrenocorticism in Nova Scotia Duck Tolling Retrievers: 25 cases (1994-2006).Semantic proximity Read ↗

A novel mutation in PRKAR1A gene in a patient with Carney complex presenting with pituitary macroadenoma, acromegaly, Cushing's syndrome and recurrent atrial myxoma.Semantic proximity Read ↗

A review of the genetics of hypoadrenocorticism.Semantic proximity Read ↗

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodentsSemantic proximity Read ↗

MHC class II association study in eight breeds of dog with hypoadrenocorticism.Semantic proximity Read ↗

PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.