Article
The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects.
Journal of human genetics - 1 Nov 2017
Trezzi Vittoria, Forni Diego, Giorda Roberto, Villa Marco, Molteni Massimo, Marino Cecilia, Mascheretti Sara
Abstract excerpt
Developmental dyslexia (DD) is a complex heritable condition characterized by impaired reading abilities. Two well-replicated candidate risk factors are as follows: (1) regulatory element associated with dyslexia 1 (READ1), which is located in intron 2 of DCDC2 and acts as a binding site for protein regulation of DCDC2 expression; and (2) a three-single-nucleotide polymorphism risk haplotype spanning KIAA0319....
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