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Article

Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.

Scientific reports - 24 Oct 2017

Ano Yasuhisa, Ikado Kumiko, Shindo Kazutoshi, Koizumi Hideki, Fujiwara Daisuke

Abstract excerpt

Tolerogenic dendritic cells (DCs) have the ability to induce regulatory T cells and play an important role in preventing chronic inflammatory and autoimmune diseases. We have identified a novel compound, 14-dehydroergosterol, from Koji, a Japanese traditional food material fermented with fungi. 14-dehydroergosterol is an ergosterol analogue with a conjugated double bond, but the activity of 14-dehydroergosterol...

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Identifiers

PMID: 29066789
DOI: 10.1038/s41598-017-14446-1
PMCID: PMC5654777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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