Article
Molecular characterization of hepatitis C virus in end-stage renal disease patients under hemodialysis.
Journal of medical virology - 1 Mar 2018
Alves da Silva Rafael, de Souza Todão Jardelina, Kamitani Fernando Luiz, Silva Antonio Eduardo Benedito, de Carvalho-Filho Roberto José, Ferraz Maria Lucia Cardoso Gomes, de Carvalho Isabel Maria Vicente Guedes
Abstract excerpt
New direct-acting antiviral (DAA) agents are in development or already approved for the treatment of chronic hepatitis C virus (HCV) infection. The effectiveness of these drugs is related to the previous existence of resistant variants. Certain clinical conditions can allow changes in immunological characteristics of the host and even modify genetic features of viral populations. The aim of this study was to...
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