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Article

Maternal Glucocorticoid Elevation and Associated Fetal Thymocyte Apoptosis are Involved in Immune Disorders of Prenatal Caffeine Exposed Offspring Mice.

Scientific reports - 23 Oct 2017

Liu Han-Xiao, Chen Ting, Wen Xiao, Qu Wen, Liu Sha, Yan Hui-Yi, Hou Li-Fang, Ping Jie

Abstract excerpt

Our previous study showed that prenatal caffeine exposure (PCE) could induce intrauterine growth retardation (IUGR) and glucocorticoid elevation in the fetus. Researchers suggested that IUGR is a risk factor for T helper cell (Th)1/Th2 deviation. However, whether PCE can induce these immune disorders and the underlying mechanisms of that induction remain unknown. This study aimed to observe the effects of PCE on...

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Identifiers

PMID: 29062003
DOI: 10.1038/s41598-017-14103-7
PMCID: PMC5653827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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