Article
PER3 VNTR polymorphism in Multiple Sclerosis: A new insight to impact of sleep disturbances in MS.
Multiple sclerosis and related disorders - 1 Oct 2017
Golalipour Masoud, Maleki Zahra, Farazmandfar Touraj, Shahbazi Majid
Abstract excerpt
BACKGROUND: Multiple Sclerosis (MS) is a degenerative disease of central nervous system caused by an immune response against the myelin. About half of MS patients suffers from sleep disturbances. The circadian clock genes such as PER3 controls circadian rhythm and sleep. Due to the role of PER3 in sleep disturbances and regulation of immune response, it is possible that PER3 dysregulation increase risk of MS...
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