Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J.

Vaccine - 4 Dec 2017

Wang Xiaoyu, Zhou Defang, Wang Guihua, Huang Libo, Zheng Qiankun, Li Chengui, Cheng Ziqiang

Abstract excerpt

The hypervariable antigenicity and immunosuppressive features of avian leukosis virus subgroup J (ALV-J) has led to great challenges to develop effective vaccines. Epitope vaccine will be a perspective trend. Previously, we identified a variant antigenic neutralizing epitope in hypervariable region 1 (hr1) of ALV-J, N-LRDFIA/E/TKWKS/GDDL/HLIRPYVNQS-C. BLAST analysis showed that the mutation of A, E, T and H in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Viral
Share to Antigenic Variation
Share to Avian Leukosis Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunogenicity, Vaccine

Share to Neutralization Tests

Share to Poultry Diseases

Share to Viral Envelope Proteins

Share to Viral Vaccines

Source

Identifiers

PMID: 29054728
DOI: 10.1016/j.vaccine.2017.10.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J.PMID 29054728Read ↗

A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genesSemantic proximity Read ↗

Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virusSemantic proximity Read ↗

Molecular epidemiology of J-subgroup avian leukosis virus isolated from meat-type chickens in southern China between 2013 and 2014.Semantic proximity Read ↗

Diversity and evolution analysis of glycoprotein GP85 from avian leukosis virus subgroup J isolates from chickens of different genetic backgrounds during 1989-2016: Coexistence of five extremely different clusters.Semantic proximity Read ↗

Diversity of Avian leukosis virus subgroup J in local chickens, Jiangxi, China.Semantic proximity Read ↗

Gp85 genetic diversity of avian leukosis virus subgroup J among different individual chickens from a native flock.Semantic proximity Read ↗

Isolation and Identification of Subgroup J Avian Leukosis Virus Inducing Multiple Systemic Tumors in Parental Meat-Type ChickensSemantic proximity Read ↗

Molecular characterization of avian leukosis virus subgroup J in Chinese local chickens between 2013 and 2018Semantic proximity Read ↗

Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009–2013 and selection of a candidate vaccine strain with broad cross-reactivitySemantic proximity Read ↗

Progress and Challenges toward the Development of Vaccines against Avian Infectious BronchitisSemantic proximity Read ↗

A conserved multi-epitope-based vaccine designed by targeting hemagglutinin protein of highly pathogenic avian H5 influenza virusesSemantic proximity Read ↗

Modification of neutralizing epitopes of hemagglutinin for the development of broadly protective H9N2 vaccine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.