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Article

Genes, pathways, and animal models in primary open-angle glaucoma.

Eye (London, England) - 1 Oct 2015

Iglesias A I, Springelkamp H, Ramdas W D, Klaver C C W, Willemsen R, van Duijn C M

Abstract excerpt

Glaucoma is an optic neuropathy characterized by loss of retinal ganglion cells (RGCs) and consequently visual field loss. It is a complex and heterogeneous disease in which both environmental and genetic factors play a role. With the advent of genome-wide association studies (GWASs), the number of loci associated with primary open-angle glaucoma (POAG) have increased greatly. There has also been major progress...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26315706
DOI: 10.1038/eye.2015.160
PMCID: PMC4815694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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