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Article

Association between gestational diabetes mellitus exposure and childhood adiposity is not substantially explained by offspring genetic risk of obesity.

Diabetic medicine : a journal of the British Diabetic Association - 1 Dec 2017

Raghavan S, Zhang W, Yang I V, Lange L A, Lange E M, Fingerlin T E, Dabelea D

Abstract excerpt

AIM: To examine the extent to which offspring obesity-associated genetic risk explains the association between gestational diabetes mellitus and childhood adiposity. METHODS: We studied 282 children aged 7-12 years who were enrolled in the Exploring Perinatal Outcomes in Children Study. A genetic risk score for BMI was calculated as the count of 91 established BMI-raising risk alleles. Multivariable linear and...

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Adiposity
Birth Weight
Cohort Studies
Diabetes, Gestational
Infant, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pediatric Obesity

Prenatal Exposure Delayed Effects

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PMID: 29048747
DOI: 10.1111/dme.13529
PMCID: PMC6880873

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