Article
Prediction of Local Transmission of Mycobacterium tuberculosis Isolates of a Predominantly Beijing Lineage by Use of a Variable-Number Tandem-Repeat Typing Method Incorporating a Consensus Set of Hypervariable Loci.
Journal of clinical microbiology - 1 Jan 2018
Murase Yoshiro, Izumi Kiyohiko, Ohkado Akihiro, Aono Akio, Chikamatsu Kinuyo, Yamada Hiroyuki, Igarashi Yuriko, Takaki Akiko, Mitarai Satoshi
Abstract excerpt
Strain genotyping based on the variable-number tandem repeat (VNTR) is widely applied for identifying the transmission of Mycobacterium tuberculosis A consensus set of four hypervariable loci (1982, 3232, 3820, and 4120) has been proposed to improve the discrimination of Beijing lineage strains. Herein, we evaluated the utility of these four hypervariable loci for tracing local tuberculosis transmission in 981...
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