Article
A quantitative and efficient approach to select MIRU-VNTR loci based on accumulation of the percentage differences of strains for discriminating divergent Mycobacterium tuberculosis sublineages.
Emerging microbes & infections - 26 Jul 2017
Pan Xin-Ling, Zhang Chun-Lei, Nakajima Chie, Fu Jin, Shao Chang-Xia, Zhao Li-Na, Cui Jia-Yi, Jiao Na, Fan Chang-Long, Suzuki Yasuhiko, Hattori Toshio, Li Di, Ling Hong
Abstract excerpt
Although several optimal mycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) loci have been suggested for genotyping homogenous Mycobacterium tuberculosis, including the Beijing genotype, a more efficient and convenient selection strategy for identifying optimal VNTR loci is needed. Here 281 M. tuberculosis isolates were analyzed. Beijing genotype and non-Beijing genotypes were...
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