Article
In Vivo Characterizations of the Immune Properties of Sericin: An Ancient Material with Emerging Value in Biomedical Applications.
Macromolecular bioscience - 1 Dec 2017
Jiao Zhanying, Song Yu, Jin Yang, Zhang Cheng, Peng Dong, Chen Zhenzhen, Chang Panpan, Kundu Subhas C, Wang Guobin, Wang Zheng, Wang Lin
Abstract excerpt
The biosafety of sericin remains controversial. The misunderstanding regarding sericin causing adverse biological responses have been clarified by extensively reviewing relevant literatures and experimentally demonstrating that sericin exhibits mild inflammatory responses, negligible allergenicity, and low immunogenicity in vivo. This study supports that sericin is biosafe as a natural biomaterial.
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