Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Task demands, tDCS intensity, and the COMT val158met polymorphism impact tDCS-linked working memory training gains.

Scientific reports - 18 Oct 2017

Stephens Jaclyn A, Jones Kevin T, Berryhill Marian E

Abstract excerpt

Working memory (WM) training paired with transcranial direct current stimulation (tDCS) can improve executive function in older adults. The unclear mechanism of tDCS likely depends on tDCS intensity, and task relevant genetic factors (e.g., for WM: COMT val158met, DAT, BDNF val66met). Higher tDCS intensity does not always lead to greater cognitive gains, and genetic polymorphisms may modulate tDCS-linked WM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Amino Acid Substitution
Share to Analysis of Variance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Learning

Share to Memory, Short-Term

Share to Polymorphism, Genetic

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29044248
DOI: 10.1038/s41598-017-14030-7
PMCID: PMC5647397

Genes

COMT
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Task demands, tDCS intensity, and the COMT val158met polymorphism impact tDCS-linked working memory training gains.PMID 29044248Read ↗

Older Adults Improve on Everyday Tasks after Working Memory Training and Neurostimulation.Semantic proximity Read ↗

Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism.Semantic proximity Read ↗

Effects of transcranial direct current stimulation (tDCS) combined with cognitive therapy in individuals with cognitive impairment: a systematic review and meta-analysisSemantic proximity Read ↗

Age-dependent Effects of Titrating Anodal Transcranial Direct Current Stimulation (tDCS) Intensity on Motor Sequence LearningSemantic proximity Read ↗

COMT rs4680 Met is not always the 'smart allele': Val allele is associated with better working memory and larger hippocampal volume in healthy Chinese.Semantic proximity Read ↗

Effects of transcranial direct current stimulation (tDCS) on cognition in older adults with mild cognitive impairment: A study protocol for a randomized controlled trialSemantic proximity Read ↗

BDNF and COMT polymorphisms have a limited association with episodic memory performance or engagement in complex cognitive activity in healthy older adults.Semantic proximity Read ↗

Sex differences in verbal working memory performance emerge at very high loads of common neuroimaging tasks.Semantic proximity Read ↗

BDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment.Semantic proximity Read ↗

Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT Val¹⁵⁸Met polymorphism.Semantic proximity Read ↗

The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition.Semantic proximity Read ↗

Working memory plasticity modulated by dopamine transporter genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.