Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre-clinical models.

The Prostate - 1 Dec 2017

Woods-Burnham Leanne, Basu Anamika, Cajigas-Du Ross Christina K, Love Arthur, Yates Clayton, De Leon Marino, Roy Sourav, Casiano Carlos A

Abstract excerpt

BACKGROUND: Understanding how biological factors contribute to prostate cancer (PCa) health disparities requires mechanistic functional analysis of specific genes or pathways in pre-clinical cellular and animal models of this malignancy. The 22Rv1 human prostatic carcinoma cell line was originally derived from the parental CWR22R cell line. Although 22Rv1 has been well characterized and used in numerous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to Cell Line, Tumor

Share to Healthcare Disparities

Share to Polymorphism, Single Nucleotide

Share to Prostatic Neoplasms

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 29030865
DOI: 10.1002/pros.23437
PMCID: PMC5687283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre-clinical models.PMID 29030865Read ↗

The Impact of African Ancestry on Prostate Cancer Disparities in the Era of Precision MedicineSemantic proximity Read ↗

Minireview: the molecular and genomic basis for prostate cancer health disparities.Semantic proximity Read ↗

Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations.Semantic proximity Read ↗

Ancestry-defined molecular taxonomy of prostate cancer.Semantic proximity Read ↗

Genetic ancestry, self-reported race and ethnicity in African Americans and European Americans in the PCaP cohort.Semantic proximity Read ↗

Expanding the Prostate Cancer Cell Line Repertoire with ACRJ-PC28, an AR-negative Neuroendocrine Cell Line Derived From an African-Caribbean PatientSemantic proximity Read ↗

Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European genetic ancestry.Semantic proximity Read ↗

Racial Disparity in Utilizing Genetic Testing for Personalized Care of Prostate CancerSemantic proximity Read ↗

Alterations in the Epigenetic Machinery Associated With Prostate Cancer Health DisparitiesSemantic proximity Read ↗

Alterations in the Epigenetic Machinery Associated with Prostate Cancer Health DisparitiesSemantic proximity Read ↗

PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry.Semantic proximity Read ↗

Precision medicine targets for prostate cancers in African American menSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.