Article
Use of genomic and functional analysis to characterize patients with steroid-resistant nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Oct 2018
Kitzler Thomas M, Kachurina Nadezda, Bitzan Martin M, Torban Elena, Goodyer Paul R
Abstract excerpt
BACKGROUND: Children with genetic causes of steroid-resistant nephrotic syndrome (SRNS) usually do well after renal transplantation, while some with idiopathic SRNS show recurrence due to a putative podocyte-toxic factor. Distinguishing different forms of SRNS based on clinical criteria has been difficult. The aim of our study was to test a novel approach that allows categorization of patients into clinically...
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