Article
Autosomal dominant polycystic kidney disease: the changing face of clinical management.
Lancet (London, England) - 16 May 2015
Ong Albert C M, Devuyst Olivier, Knebelmann Bertrand, Walz Gerd
Abstract excerpt
Autosomal dominant polycystic kidney disease is the most common inherited kidney disease and accounts for 7-10% of all patients on renal replacement therapy worldwide. Although first reported 500 years ago, this disorder is still regarded as untreatable and its pathogenesis is poorly understood despite much study. During the past 40 years, however, remarkable advances have transformed our understanding of how the...
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