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Article

Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles.

PloS one - 1 Jan 2017

Andersson Erik, Bergemalm Daniel, Kruse Robert, Neumann Gunter, D'Amato Mauro, Repsilber Dirk, Halfvarson Jonas

Abstract excerpt

OBJECTIVE: Genetic and immunological data indicate that inflammatory bowel disease (IBD) are characterized by specific inflammatory protein profiles. However, the serum proteome of IBD is still to be defined. We aimed to characterize the inflammatory serum protein profiles of Crohn's disease (CD) and ulcerative colitis (UC), using the novel proximity extension assay. METHODS: A panel of 91 inflammatory proteins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28982144
DOI: 10.1371/journal.pone.0186142
PMCID: PMC5628935

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