Article
Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation.
Cancer research communications - 28 Nov 2023
Guyonnet Emma, Kim Shana J, Xia Yue Yin, Giannakeas Vasily, Lubinski Jan, Randall Armel Susan, Eisen Andrea, Bordeleau Louise, Eng Charis, Olopade Olufunmilayo I, Tung Nadine, Foulkes William D, Couch Fergus J, Aeilts Amber M, Narod Steven A, Kotsopoulos Joanne
Abstract excerpt
In the general population, physical activity has been associated with a lower risk of several cancers; however, the evidence for ovarian cancer is not clear. It is suggested that early-life physical activity may differentially impact risk. Whether this is true among women at high risk due to a pathogenic variant (mutation) in the BRCA1 or BRCA2 genes has not been evaluated. Thus, we performed a matched...
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