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Article

Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation.

Journal of dental research - 1 Feb 2018

Xu J G, Gong T, Wang Y Y, Zou T, Heng B C, Yang Y Q, Zhang C F

Abstract excerpt

Low efficiency of deriving endothelial cells (ECs) from adult stem cells hampers their utilization in tissue engineering studies. The purpose of this study was to investigate whether suppression of transforming growth factor beta (TGF-β) signaling could enhance the differentiation efficiency of dental pulp-derived stem cells into ECs. We initially used vascular endothelial growth factor A (VEGF-A) to stimulate 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28972822
DOI: 10.1177/0022034517733741
PMCID: PMC6429570

Genes

SMAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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